Lay the genetic foundation for your healthiest future.

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About our technology.

We’ve developed a gene therapy platform accelerating human genetic enhancement and longevity. 

Our gene therapy is administered via non-invasive injection.

A health professional from a Minicircle clinical partner will administer the plasmid gene therapy via subcutaneous fat injection. After injection, you’ll be monitored for 30 minutes. The overall procedure doesn’t take longer than an hour and effects are estimated to last approximately one year.

Plasmid DNA is combined with a transformation reagent to allow for cellular absorption.

Minicircle’s technology uses episomal DNA plasmids to deliver specific genes into human cells. These plasmids remain outside the chromosome, meaning they do not integrate into your DNA. Prior to injection, DNA is complexed with a transformation reagent for 30 minutes to be prepared for absorption by the cell.

After the plasmid is absorbed into the cell, proteins are secreted to deliver benefits.

After administration, the plasmid complex is taken up by cells, and a portion reaches the nucleus, where the genetic instructions are transcribed and translated into proteins. The proteins produced are secreted into the bloodstream, allowing for systemic, whole-body effects. Our current gene library focuses on proteins with potential roles in muscle development, metabolic function, cognitive health, and cellular resilience.

AAV Gene Therapy
Last ~ 1 year
Permanent
Safe, repeatable dosing
Dangerous, requires immunosuppression
Single, non-invasive injection
Complex, invasive administration
Comparatively accessible
Prohibitively expensive
Stable at room temperature
Requires -80°C cryostorage
Designed for universal adoption
Only for rare diseases

Explore our therapies.

Address health concerns, enhance abilities, and promote longevity with Minicircle’s modern gene therapy.

Follistatin

FST-344

Potential benefits include:

  • Increase lean mass
  • Reduce body fat percentage
  • Lower epigenetic age
  • Improve overall wellbeing

Klotho

Coming 2026

Potential benefits include:

  • Promote longevity
  • Enhance cognitive function
  • Improve cardiovascular health
  • Support kidney health

How it works.

Pursue your purpose with Minicircle.
Start your journey today.

01

Contact a clinic.

Get started by contacting one of our partner clinics to make an appointment.

02

Complete testing.

Your clinician will work with you to complete necessary testing before treatment.

03

Travel to your clinic.

Depending on where you live, you may need to make travel arrangements ahead of your appointment.

04

Receive therapy.

Our therapies are administered via injection — no surgery, no downtime.

05

Stay in touch.

Share your experience and connect with others. Our team is available to answer any questions along the way.

06

Re-administer treatment.

People typically re-up their Minicircle treatment at approx. 12 months when effects wear off.